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myrmepropagandist

A new study has found a terrible bottleneck in human ancestors about 900k years ago. There were as few as 1000 individuals left ... if this is verified further there was a time when we almost didn't make it.

science.org/doi/pdf/10.1126/sc

76 comments
Ángela Stella Matutina

@futurebird

As I've said elsewhere that means we probably won't go extinct in the next few millenia. But without a global technological civilization we may wish we were.

Preston Maness ☭

@futurebird 117 thousand years with only a little over one thousand individuals? Damn. How common is it for species to stick around that long with such a low population?

Job

@aspensmonster @futurebird I dunno, but after learning how mutational meltdown killed off the last mammoth population, the fact that our ancestors survived this (assuming it holds up) sounds even more absurd

youtube.com/watch?v=vCad77_c-L

en.wikipedia.org/wiki/Mutation

Righteous Hazard

@aspensmonster @futurebird There have been other severe bottlenecks, and they are shockingly recent. As a result, homo sapiens’ genetic diversity is very low.

One thing that racists get wrong is that human inter-racial genetic diversity is simply too low to support their claims. Our diversity relative to our geographic distribution is absurdly low. Genetics-based racism isn’t just morally wrong, it is radically wrong about our reality as a species.

olav

@bertwells
@aspensmonster @futurebird

Except actual Nazis, I think most.of the racism has moved to skin color, and particularly culture. Black culture, indigenous culture, Hispanic culture, Jewish, Romany, etc. And universally it seems a bucket of anyone Muslim, from Rabat to Jakarta

The Crafty Miss

@aspensmonster 1280 is the nadir but it looks like they're positing that the 117k period started at the 100k-ish original pop, fell to 1280 at some point, then rose to the 27k-ish pop by the end of that period. It wasn't 1280 for the whole 117k years. But that's from the graphic, not reading the paper

Droid Boy :coolified:

@aspensmonster @futurebird I would assume there are quite a few birds on islands who live that Life 😄

GeePawHill

@futurebird Fascinating, I look forward to the confirmation and debate.

(For the record, we've got 8 billion or so, now, and I regard *this* as a time when we're likely not gonna make it.)

Tom Ritchford

@GeePawHill @futurebird Oh, humans will survive this. We live in more environments than roaches, and there are eight billion of us.

How many will remain though? I've read convincing articles showing that the carrying capacity of the planet without fossil fuels is around half a billion, and that's before we render the tropics mostly uninhabitable...

Not having kids is a great way to prevent then from dying in the water wars. 💔

Threadbane

@TomSwirly @GeePawHill @futurebird
The oceans are rapidly dying and we won't do well without fish, crabs, oysters, etc, birds, mammals, reptiles, fruit trees and plants that depend on beneficial symbiotic insects. I suspect we will kill each other off as food.

Alex Schroeder

@GeePawHill @futurebird I remember similar discussions of human bottlenecks when I was a student of biology in the previous millennium. Traces of the older discussion to be found in Britannica, for example:
«The variation in DNA among all the widespread human populations of today is less than what is found in any population of living apes. This is very surprising, given that there are so few apes in such small geographic areas—conditions that one might expect to produce a more homogeneous gene pool. One possible explanation is that ancestral H. sapiens quite recently passed through a “bottleneck” in which the entire human population was reduced to a few hundred or perhaps a couple of thousand individuals, perhaps approximately 150 kya; however, this explanation is not universally accepted. Nevertheless, such a population size would be sufficiently small for a set of unique traits to become established, making it plausible that one small group would be the population from which H. sapiens emerged as a new isolated reproductive entity.»
https://www.britannica.com/topic/Homo-sapiens/Modern-populations

@GeePawHill @futurebird I remember similar discussions of human bottlenecks when I was a student of biology in the previous millennium. Traces of the older discussion to be found in Britannica, for example:
«The variation in DNA among all the widespread human populations of today is less than what is found in any population of living apes. This is very surprising, given that there are so few apes in such small geographic areas—conditions that one might expect to produce a more homogeneous gene pool....

Toost

@futurebird makes you think about pandas. Those guys are just waiting to make their play.

Lev Petrovitch

@futurebird
I can't avoid it, when I see so much precision in numbers that, almost by definition, must be hard to evaluate (fewer than 1280, 27160, and 98130) my BS detector activates.

Vive_Levant

@yanncphoto @levpetrovitch @futurebird I heard that they were during the bottleneck, according to the last count, 1337.

Mark

@levpetrovitch @futurebird can you accept estimates that have some statistical uncertainty about them?

To me, 1280 could mean 1279-1281, or 1000-1500. Either way, the “precise” number is probably the centroid of their estimate. Confidence intervals usually don’t make the lede.

Job

@levpetrovitch @futurebird I mean, I get you, but on the other hand the human genome contains roughly 3 billion base pairs. I can actually imagine that you can get crazy precise estimates with that many data points per individual when comparing DNA between populations to do projections back in time

(funny enough in this context, WP first says it is an unrealistically precise 3,117,275,501 bp, then immediately contradicts it by claiming it's 3,054,815,472 bp instead en.wikipedia.org/wiki/Human_ge )

@levpetrovitch @futurebird I mean, I get you, but on the other hand the human genome contains roughly 3 billion base pairs. I can actually imagine that you can get crazy precise estimates with that many data points per individual when comparing DNA between populations to do projections back in time

(funny enough in this context, WP first says it is an unrealistically precise 3,117,275,501 bp, then immediately contradicts it by claiming it's 3,054,815,472 bp instead en.wikipedia.org/wiki/Human_ge

🏳️‍⚧️ Fiona 🏳️‍⚧️

@vanderZwan @levpetrovitch @futurebird That still doesn’t work: Everyone whose line ended up dying out by definition has not left a trace in our DNA.

Was that almost nobody? 10%? 50%? 90%?

There may even be ways to approach the answer to that, but they are by definition not in our DNA and bound to be highly imprecise.

🏳️‍⚧️ Fiona 🏳️‍⚧️

@vanderZwan @levpetrovitch @futurebird

And while I can absolutely buy that the human population was terrifyingly low at times (I believe I remember something that it may have gotten to the very low double digits at some point, creating insane evolutionary pressure), I have a much harder time to believe that it was possible to maintain these insanely low numbers for the kinds of time-periods that we are talking about here. Over 100000 years at a population of of ≈1000 people seems very implausible to me.

Job

@Fiona @levpetrovitch @futurebird well this paper is not exactly tracing lineages, it's tracing genetic drift across fifty populations, sampling about 3000 people. So it looks at the accumulation and spread of new mutations.

Of course I don't know how one makes the jump from genetic drift to population size estimates, let alone population size estimates over time, so no clue on what precision to expect there.

🏳️‍⚧️ Fiona 🏳️‍⚧️

@vanderZwan @levpetrovitch @futurebird I know a LITTLE(!) bit about that topic: If you use the so called coalescent model, you can essentially derive that genetic drift is anti-proportional to population-size (Easiest way to model this further is funnily enough to rescale time).

I gave a presentation on this as part of my masters and the slides are even online, but because they contain my dead-name and are stored on a domain that contains that as well, I’m really sorry that it is a bit too inconvenient to share them.😞︎ (It’s a really nice set of slides too, if I may say so.)

@vanderZwan @levpetrovitch @futurebird I know a LITTLE(!) bit about that topic: If you use the so called coalescent model, you can essentially derive that genetic drift is anti-proportional to population-size (Easiest way to model this further is funnily enough to rescale time).

I gave a presentation on this as part of my masters and the slides are even online, but because they contain my dead-name and are stored on a domain that contains that as well, I’m really sorry that it is a bit too inconvenient...

Job

@Fiona @levpetrovitch @futurebird aww, that's too bad but I completely understand. I will just imagine the best quality slides then.

Job

@Fiona @levpetrovitch @futurebird (I'm just having fun speculating, don't take this seriously)

I suspect it might be possible to get an estimate of how quickly lineages die out by comparing genetic drift in Y-chromosomes, which don't recombine, to the other chromosomes which do. Because the rate at which genes are filtered out of the population should be different for "gene that can only be passed father-to-son" vs "gene that can be passed any-parent-to-any-child".

🏳️‍⚧️ Fiona 🏳️‍⚧️

@vanderZwan @levpetrovitch @futurebird IIRC correctly that doesn’t actually make that much of a difference (like a constant factor or something).

I learned most of what I know on the topic from Magnus Nordborg’s paper “Coalescent Theory”, which I remember as being pretty accessible, though that may come from the perspective of someone who had received some non-zero amount of training on related topics beforehand.

You can find the paper here: cseweb.ucsd.edu/classes/sp05/c

@vanderZwan @levpetrovitch @futurebird IIRC correctly that doesn’t actually make that much of a difference (like a constant factor or something).

I learned most of what I know on the topic from Magnus Nordborg’s paper “Coalescent Theory”, which I remember as being pretty accessible, though that may come from the perspective of someone who had received some non-zero amount of training on related topics beforehand.

Rhaedas

@levpetrovitch Studies like this are very useful, but they should never be taken alone as some proof of an idea. Further evaluation and validation is needed, preferably from unrelated areas. A reminder that this is how the Toba bottleneck theory began, with a single proposal and a public acceptance that it must be true because it was a science paper. Later archeological findings put the theory as a global bottleneck into doubt.

@futurebird

Brekekekiwi

@levpetrovitch @futurebird I must admit, the number of significant figures seems remarkable. I would love to know if this study truly was this specific, and to be smart enough to follow the process they took to get there.

Bruce Heerssen

@levpetrovitch @futurebird I'm waiting for the Creationists. They'll surely have some fun with this.

Evelyn

@futurebird Person of the Bottleneck Era, comforting a friend who’s going through a bad breakup: “You’re better off without them, really. And don’t worry, there are a lot of fish in the sea.”

Friend, sniffing back tears: “No, there aren’t. There aren’t very many at all.”

Mark Maguire

@gorfram @futurebird This doesn’t freak me out too much - in fact it’s relatable. This Bottleneck kind of describes what it felt like growing up and living in Ireland. 😄

Evelyn

@MarkMaguire @futurebird I was raised a Quaker, & one time I did the math on why so few Young Friends married other Quakers. Of all the Quakers I knew of (probably around 1280 or so 🤣) at least half were women, the vast majority were middle-aged or older, & some were the middle aged-ones’ children. Of the few guys in the suitable age range, a large % were either gay or taken or my brother.

That left… four. One of them I kind of disliked; & the other 3 seemed unlikely to like me in that way.

Hjalti

@futurebird Bet we somehow managed to cause this bottleneck ourselves

Righteous Hazard

@futurebird IMO, bottlenecks like these are both interesting science and inspirational topics to go into with students. In studying them, it is possible for every student in the class to hear a message:

“We are all descended from a small group who kept humanity alive through unspeakable extinction level conditions. Every single one of you is a direct heir to the most baddass people who ever lived.”

Pauline von Hellermann

@futurebird really interesting, thank you for sharing! Made me speculate about another possible bottleneck coming up and the terrifying prospect of really only billionaires in bunkers and their offspring (already plentiful, Musk and others have 10+ children) surviving and a distant future with everyone descending from those!

Cabbidges

@pvonhellermannn @futurebird I thought about that too. A bunker is also a prison though and what emerges is going to be interbred, and unaccustomed to what remains of the earth, probably take more time to help them than it would to defeat them.

NoctisEqui 🇺🇦🇵🇸🇪🇹

@futurebird

The road not taken. I wonder what would be the dominant species in that alternate possibility. Any thoughts? Dolphins? Cave Lions? Mastodons, of course!

🍋 Superball ☀️

@NoctisEqui @futurebird

Not so sure we’re the dominant species. Destructive, sure. . . . 😏

Cyber Yuki

@superball @NoctisEqui @futurebird

Well, we're both dominant and submissive, so it evens out 🤪

Lev Petrovitch

@superball

We're the dominant species in a "whomever has the power to destroy a resource controls it" kind of way. We *definitely* have the power to destroy the biosphere

@NoctisEqui @futurebird

Samhain Night

@futurebird I'd heard about that years ago, but it was pre-internet. Thanks for the article, I've always wanted to know more about it.

Tofu Golem

@futurebird
Don't exactly that kind of bottleneck combined with changes in the environment create the perfect storm for rapid evolution?

When you have a large breeding population, a lot of beneficial mutations can simply get "washed out" in the gene pool.

It's still super cool information. We know so much more about distant human history than we ever thought we would.

DELETED

@futurebird Yeah, but on the other hand, at that time it was easy to get some peace and quiet in this place.

Greg Stolze

@futurebird I’ve seen previous suggestions that, at one time, the global human population dropped to the point that they couldn’t fill Soldier Field and honestly? I kinda want to believe it, selfishly.

1/x

Greg Stolze

@futurebird

Like, if our hairy ancestors could survive and come back to an 8bn population after some catastrophe like the Chixulub Impactor knocked them back to the size of the line for Taylor Swift tickets when she plays Madison Square Garden, it gives me hope in the face of climate change and Stage IV Capitalism.

2/x

Greg Stolze

@futurebird

“Sure, things look bad but we bounced back before and back then, our tech tree maxed out at Tamed Fire, Wheeled Cart, Pointy Stick, and if you beat the secret level, Domesticated Dog.”

I kinda need that hope right now. I’m like, “Yes! Hope! Inject it straight into my gumline, I don’t care, I’m fiending for it!”

3/3

Cyber Yuki

@futurebird Could it be possible that the inbreeding resulting from that bottleneck was the cause of so many diseases today? 🤔

myrmepropagandist

@yuki2501

It's been a long time since then so maybe not? And 1000 is just enough to get by without it getting too bad.

Cyber Yuki

@futurebird What really saddens me is that we lost the ability to produce vitamin C.

God save us if all citrus in the world are lost.

myrmepropagandist

@yuki2501

It gives us an excuse to cultivate peppers and citrus.

Michael Gemar

@yuki2501 @futurebird That’s a good target for CRISPR or other genetic engineering, as (I believe) it is controlled by a single gene in primates.

Knut Morå

@yuki2501
It will feel as vindication for all us potato-peel-eaters though!
@futurebird

ᴚ uɐᗡ

@futurebird I mean it was only what 6,000 years ago we were down to the 2 Adam and Eve did I get that right

prom™️

@futurebird This seems to coincide with the "missing link" time range - kinda remarkable. I also wonder what might have happened. Was it ecological? Did they have fire? Maybe we'll be sure one day.

Hiba

@futurebird dang nature really gave it her best shot

Jeremy (יעקב) 🇺🇦

@futurebird

Right up there with the Toba extinction 70-75,000 years ago that blacked out the sun for nearly a decade straight and left small clusters of breeding pairs available, nearly ending the species.

The unsettled period on the planet was really bad for us all.

Daydream Soundtrax

@futurebird unfortunately for most other species we did make it

Generic Sadboy 1916

@futurebird 'great filter' candidate? just from the statistics? very interesting!

Androcat

@futurebird I've sometimes wondered if our weird investments into brains might have been driven by a prolonged period of having to move from niche to niche without time for physical adaptations to really pay off.

People tend to think brains are great, but in the animal kingdom in general, it seems brains are ranked below a really effective digestive tract in terms of evolutionary payouts.

Ken Tindell

@futurebird @glynmoody *homer bart gif* “_another_ time when we almost didn’t make it”

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