@grishka I'm not sure I need to worry about that kind of optimization just yet. Whatever you might think, an individual server will never grow to the size of a VK. Worrying about it before you're 1% of the way there is not going to help you I believe.
@mariusor individual server? No. Most (all?) fediverse projects won't scale to a typical high-load infrastructure — most you could do is have the DB on a separate server. But you absolutely can have thousands, and even millions, of followers from all over the fediverse. Eugen, for example, has 467586 followers.