@mariusor individual server? No. Most (all?) fediverse projects won't scale to a typical high-load infrastructure — most you could do is have the DB on a separate server. But you absolutely can have thousands, and even millions, of followers from all over the fediverse. Eugen, for example, has 467586 followers.
@mariusor I have "just" 200 followers on my Smithereen account, and it's already mildly frightening to watch the log as it spams each post at several tens of servers lol