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There is a wrestler, Khelif, who transphobes are getting angry at, for having elevated testosterone (even though she was on meds that lower T), and claiming she's XY. I don't know if the XY thing is true, but even if it were, it would be an inactive Y since she was born with a uterus and stuff. But it reminds me of something interesting one of my professors mentioned years ago in college, 7 comments
I think it would be interesting if similar tests were done on male athletes and it turns out there's a bunch of XXY or XXXY males. @amorphophalex I recently learned of someone who went her whole life unaware she had down syndrome because she didn’t present with the usual physical characteristics in fact, this is possibly the case with a lot of chromosomal abnormalities aside from the sex chromosomes, but the sex chromosomes already have random X-inactivation programmed within them. As long as you have at least one X, you're fine (no X's and you're dead because the genes on the X chromosome are, interestingly, unrelated to genitals or sex differentiation. those are scattered elsewhere in the genome. lol)  @amorphophalex Always remember to collect as many X chromosomes as possible so you can see the color red good @amorphophalex Alex I love it when my blood clots in the the exact amounts and locations I am expecting it to clot |
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which is that it's likely LOTS of people have sex chromosome abnormalities and we just don't know it, because not everyone gets their chromosomes looked at. And a lot of early assumptions about sex chromosomes--like that it automatically leads to infertility or mental slowness and stuff--is likely biased because the only people getting tested were people who had some kind of health issue prompting the test.