@darius My daily is a 2016 MBP (2.7GHz i7, 16GB RAM, Radeon 460) running macOS 12.3.1. I haven't noticed any performance issues, but I've always stayed current and probably wouldn't notice gradual degradation. Still, I'm happy enough that I haven't felt a need for a new machine.

For science, I did a brew update && brew upgrade this morning -- 53 formulae and 1 cask without issue.