One of the cool things with 2-bit illustration that I noticed.
If I save the drawing at twice the resolution(1024x640) that I'm drawing it in(512x320), downsizing it from the jpg to a tga and re-importing it is nearly lossless, I see maybe one or two confused pixels of loss during the compression from a 80% jpg.
It means that I can always recover my work from a jpg at 200% resolution if I loose the chr source file.
@neauoire I wonder if you'd have even better luck using like PNG-8 instead of JPG. Possibly smaller files, too!