@Impossible_PhD @KevinLikesMaps
Could probably scare up that many in a large university city like KWC, but even with the projected rates of 1% or so (I do think 5% is a bit pessimistic), there are also the troubles of finding those who aren't already on HRT and willing to engage in such a study. We're consistently in a Catch-22 bind.
SO many eggs I wish could be helped...
@theogrin @KevinLikesMaps Let's do math here with NYC, population 8.4m.
1.6% are trans, and 20% of that are trans men (20% are trans women, 60% are nonbinary). That's 26,880 trans men in NYC. Of those, you need *only* those who are having SI (~40%), so 10,752. Of that, you need the folks who want HRT (~33%), for 3,548. Of THOSE, you need the guys who have not yet begun HRT, but have decided to get it. Then, only those who are willing to do an RCT.
That is a SMALL population, isn't it?