That's a deep question!
Given the ability of our DNA to alter and therefore produce subtle and not so subtle differences in the resulting human, doesn't it mean that the nature side of our psyche can be different also resulting in further change in the nurtured psyche.
Not sure where the destructive aspect first showed itself or why. The gold rush would be a good example but there must be earlier examples. Greed is so destructive. It would be fascinating to find out.
@StevePLMarquis
It's interesting though to understand the sage and moral behavior of indigenious people. I'm really intrigued by their ability to build a friendly relationship with nature.