If you missed it, @soatok is writing a proposal for E2EE over Mastodon/ActivityPub for DMs, which IMHO is heaps better and more adhering to the Fediverse spirit than relying over a centralized and third party clients unfriendly application
Relevant repo with the specs: https://github.com/soatok/mastodon-e2ee-specification
Relevant repo with the specs: https://github.com/soatok/mastodon-e2ee-specification