I'm really impressed by nanodjango (by @radiac, presented in a lightning talk at #djangoconUS just now) - it's the latest in a long line of attempts to have Django work for Flask-style single file apps but it's got WAY more features than previous attempts I've seen, like model and admin support and even async
My notes here: https://simonwillison.net/2024/Sep/24/nanodjango/
nanodjango docs and tutorial: https://nanodjango.readthedocs.io/
The getting started fits in a single image