EFF's "privacy badger" extension today expanded its effects on your Chrome settings to disable the Google "Ad Sandbox". This disables not just Topics (the worst of Ad Sandbox's features so far) but also the other two features— including "Ad Measurement", a feature that Apple copied a couple years back and Firefox adopted as an "experiment" this month.
https://mastodon.social/@eff/112831156838249955
The EFF here succinctly argues why all of these ad features should not be running on your computer:
@hrbrmstr I know you've been following this closely -- is Privacy Badger now doing everything that can be done to manage Chrome?