So how can this fail? In a huge number of ways. Circuits age with time and use. The ability of the individual capacitors to hold the charge goes down slowly over time, the transistors in the sense amplifiers degrade, points of contact oxidize, etc... Past a certain point this can make the whole process end up outside of the thresholds required to reliably read, write and retain the bits in memory. 4/17
This can lead to different failures: a very common one is a stuck bit, which ends up being always read as 1 or 0, regardless of what was written into it. Another type is timing-dependent failures, which cause a bit to flip but only if it's not touched in due time by an access or a refresh. More catastrophic errors can affect entire lines - which is what happens when a sense amplifier starts to fail. 5/17