The only thing that irritates me about @thunderbird ‘Supernova’ is that the subjects of emails in the new list view have a slightly bolder-than-normal font weight (500 instead of 400), and now I always think I have a bunch of unread emails. Since the subject line is already bigger than the sender's name, there is no need for a separate weight.
@thunderbird I hope the team will take this into consideration, but for now it's nothing a userChrome can't fix 😉