@ephemeromorph "Researchers have tentatively suggested that [progesterone] form 2 became gradually harder to produce around 1975, based on a review of production difficulties documented or alluded to in existing literature."

positively lovecraftian implications.

someone's going to synthesize a thing and its going to cause one of our neurotransmitters to pop into a lower-energy polymorph that works the same but is several orders-of-magnitude more delicious-smelling to the old ones, crikey